Association of MMP3 and TIMP2 promoter polymorphisms with nonsyndromic oral clefts
نویسندگان
چکیده
منابع مشابه
Lack of association between IRF6 polymorphisms and nonsyndromic oral clefts in South Indian population
Objec ve: This present study is aimed to inves gate the associa on between interferon regulatory factor 6 (IRF6), single nucleo de polymorphisms (SNPs), and nonsyndromic cle lip without without cle palate (NSCLP) in the South Indian popula on. Subject and Methods: For this study, 190 unrelated NSCLP pa ents and 189 controls with‐ out cle s were genotyped with rs2235371 (V274...
متن کاملAssociation between PAX7 and NTN1 gene polymorphisms and nonsyndromic orofacial clefts in a northern Chinese population
BACKGROUND Nonsyndromic orofacial clefts (NSOC) are the most common orofacial congenital defect with a complex etiology. Genome-wide association studies have identified paired box protein 7 (PAX7) and netrin-1 (NTN1) as candidate susceptibility genes for NSOC in both European and Asian populations. Here, possible associations between single-nucleotide polymorphisms (SNPs) in or near PAX7 and NT...
متن کاملAssociation between the transforming growth factor alpha gene and nonsyndromic oral clefts: a HuGE review.
Transforming growth factor alpha (TGFA) is a well-characterized mammalian growth factor. Since the first report of an association between DNA sequence variants at the TGFA genetic locus and nonsyndromic oral clefts, 47 studies have been carried out, producing conflicting results. In this review, the author synthesizes findings from published reports on the association between the TGFA gene and ...
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چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولAssociation between MMP3 and TIMP3 polymorphisms and risk of osteoarthritis
Osteoarthritis (OA) is the most commonly occurring degenerative joint disease worldwide, and its incidence has increased in recent years. We evaluated whether there is the association between MMP-3 and TIMP-3 variants and susceptibility to OA in a Chinese population. Venous blood samples were collected from 431 female participants (200 cases and 231 controls) at Hong Hui Hospital, Xi'an Jiaoton...
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ژورنال
عنوان ژورنال: Birth Defects Research Part A: Clinical and Molecular Teratology
سال: 2012
ISSN: 1542-0752
DOI: 10.1002/bdra.23026